Mycophenolic Acid and Metabolite
Test ID:
703853
CPT code:
80180
Synonyms:
•Myfortic®
Clinical Use:
Monitor therapeutic levels; evaluate toxicity
Test Information:
Mycophenolic acid (MPA) is the active metabolite of the prodrug, mycophenolate mofetil (MMF). Absorption of the prodrug is rapid following oral administration to the extent that detectable levels are not seen. Similar effects are observed after cessation of IV administration. Once formed, MPA undergoes metabolism to form the pharmacologically inactive phenolic glucuronide metabolite, MPAG. In vivo, MPAG is converted to MPA via enterohepatic recirculation, which results in a secondary peak in the plasma concentration time profile.1 MPA and MPAG are 92% and 87% protein bound, respectively, at usual clinical concentrations.
Specimen Type:
Serum or plasma
Requested Volume:
1.2mL
Minimum Volume:
0.3 mL
Container Type:
Red-top tube or lavender-top (EDTA) tube
Collection:
Transfer separated serum or plasma to a plastic transport tube.
Storage Instructions:
Room temperature
Stability Requirements:
Temperature | Period |
---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Rejection Criteria
Gel-barrier tube
Return Back to Test Directory
MCI Diagnostic
Providing top patient care with fast results.
Hours of Operation
Mon - Sat: 7 AM-11 PM
Sun: 7 AM-3 PM
COVID-19 Drive-Thru Hours
Mon-Fri: 9 AM-6 PM
Federal Holidays - CLOSED
More Information - Click Here
Government Contract
DUNS # 125722608
Cage Code: 3FPQ3
COVID-19
COVID-19 Fee & Pricing