Tricyclic Antidepressants, Plasma
Test ID:
706711
CPT code:
80337
Synonyms:
Tricyclic Antidepressants Screen, Serum or Plasma
Clinical Use:
Detect the presence of tricyclic antidepressants
Test Information:
Tricyclic antidepressants are prescribed for the treatment of endogenous depression and neuralgic pain disorders. The tricyclic antidepressants include amitriptyline, imipramine, doxepin, and their demethylated metabolites, nortriptyline and desipramine. The tricyclic antidepressants block neuronal uptake of norepinephrine and serotonin. The degree of inhibition seems to correlate with antidepressant activity. These drugs also have sedative effects.
Specimen Type:
Serum or plasma
Requested Volume:
2 mL
Minimum Volume:
0.6 mL
Container Type:
Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
Collection:
Transfer separated serum or plasma to a plastic transport tube.
Storage Instructions:
Refrigerate.
Stability Requirements:
Temperature |
Period |
---|---|
Room temperature |
3 days |
Refrigerated |
1 month |
Frozen |
3 months |
Rejection Criteria
Gel-barrier tube
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