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Total Glutathione

Test ID: 

704356

CPT code:

82978

Clinical Use:

Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson’s disease, HIV, liver disease, renal failure, as well as preëclampsia.

Specimen Type:

Whole blood

Requested Volume: 

500 μL

Minimum Volume: 

100 μL

Container Type: 

Yellow-top ACD-B tube (acid citrate dextrose) or yellow-top ACD-A tube

Storage Instructions:

Room temperature

Stability Requirements:

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

7 days

Rejection Criteria

Blood collected in tubes other than ACD tubes; hemolyzed specimens; clotted specimens

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