Thyroid Peroxidase (TPO) Antibodies

Test ID: 

704314

CPT code:

86376

Synonyms:

Antimicrosomal Antibody
Antithyroid Microsomal Antibody

Clinical Use:

Differential diagnosis of hypothyroidism and thyroiditis

Test Information:

Antibodies to thyroid microsomes (thyroid peroxidase) are present in 70% to 90% of patients with chronic thyroiditis. They are also present in smaller percentages of patients of other thyroid diseases. Antibody production may be confined to lymphocytes within the thyroid, and serum may be negative. Small numbers (3%) of people with no evidence of disease may have antibody. This is more frequent in females and increases with age.

Specimen Type:

Serum

Requested Volume: 

0.8 mL

Minimum Volume: 

0.3 mL

Container Type: 

Red-top tube or gel-barrier tube

Collection:

If red-top tube is used, transfer separated serum to a plastic transport tube.

Storage Instructions:

Room temperature

Stability Requirement:

Temperature                           Period
Room temperature                 14 days
Refrigerated                             14 days
Frozen                                       14 days

Rejection Criteria

Citrate plasma specimen; improper labeling