Thyroid Peroxidase Antibodies (Anti-TPO)

Test ID: 

704196

CPT code:

86376

Synonyms:

Antimicrosomal Antibody
Antithyroid Microsomal Antibody

Clinical Use:

Differential diagnosis of hypothyroidism and thyroiditis

Test Information:

Antibodies to thyroid microsomes (thyroid peroxidase) are present in 70% to 90% of patients with chronic thyroiditis. They are also present in smaller percentages of patients of other thyroid diseases. Antibody production may be confined to lymphocytes within the thyroid, and serum may be negative. Small numbers (3%) of people with no evidence of disease may have antibody. This is more frequent in females and increases with age.

Specimen Type:

Serum

Requested Volume: 

0.8 mL

Minimum Volume: 

0.3 mL (Note: This volume does not allow for repeat testing.)

Container Type: 

Red-top tube or gel-barrier tube

Patient Preparation: 

Room temperature

Collection:

If red-top tube is used, transfer separated serum to a plastic transport tube.

Storage Instructions:

Room temperature

Stability Requirement:

Temperature                                 Period
Room temperature                      14 days
Refrigerated                                  14 days
Frozen                                            14 days

Rejection Criteria

Citrate plasma specimen; improper labeling