Drugs of abuse testing
Propoxyphene is an analgesic structurally similar to methadone. Its metabolite, norpropoxyphene is also pharmacologically active. Toxic effects include nausea, vomiting, and progressive central nervous system depression. Peak serum level occurs two hours postural dose, half-life is 8 to 24 hours. Propoxyphene can also be measured in urine as part of a drug of abuse test.
Use plastic urine drug bottle and tamper-evident seal for forensic specimen. Collection kits are available by request from the laboratory.
Urine temperature monitoring is recommended for samples to be tested for medicolegal purposes.
Maintain specimen at room temperature. If arrival extends beyond seven days, then refrigerate.
Quantity not sufficient for analysis; improper specimen (serum, plasma, blood); incomplete chain-of-custody documentation; incomplete specimen identification.