Oxcarbazepine (Trileptal)

Test ID: 

703888

CPT code:

80183

Synonyms:

GP 47680

Trileptal®

Oxcarbazepine, Serum or Plasma

Clinical Use:

Oxcarbazepine is an antiepileptic drug, indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy. It is used in adjunctive therapy in epileptic children between the ages of four and 16.

Test Information:

Oxcarbazepine is the prodrug for its active metabolite, 10-hydroxy-carbamazepine (MHD). MHD reaches maximal serum concentrations in three to five hours after oral ingestion and is 40% bound to protein. The elimination half-life is 8 to 15 hours. Co-administration of other antiepileptic drugs (eg, carbamazepine, phenytoin, phenobarbital, primidone) causes decreases in MHD serum levels

Specimen Type:

Serum or plasma

Requested Volume: 

1 mL

Minimum Volume: 

0.3 mL

Container Type: 

Serum or plasma

Collection:

Transfer separated serum or plasma to a plastic transport tube. Draw trough levels immediately prior to next dose. Steady-state levels are reached within two to three days in patients taking oxcarbazepine twice daily

Storage Instructions:

Room temperature

Stability Requirements:

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

105 days

Freeze/thaw cycles

Stable x3

Rejection Criteria:

Gross lipemia; hemolysis; icteric specimen; gel-barrier tube

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