Oxcarbazepine (Trileptal)

Test ID: 


CPT code:



GP 47680


Oxcarbazepine, Serum or Plasma

Clinical Use:

Oxcarbazepine is an antiepileptic drug, indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy. It is used in adjunctive therapy in epileptic children between the ages of four and 16.

Test Information:

Oxcarbazepine is the prodrug for its active metabolite, 10-hydroxy-carbamazepine (MHD). MHD reaches maximal serum concentrations in three to five hours after oral ingestion and is 40% bound to protein. The elimination half-life is 8 to 15 hours. Co-administration of other antiepileptic drugs (eg, carbamazepine, phenytoin, phenobarbital, primidone) causes decreases in MHD serum levels

Specimen Type:

Serum or plasma

Requested Volume: 

1 mL

Minimum Volume: 

0.3 mL

Container Type: 

Serum or plasma


Transfer separated serum or plasma to a plastic transport tube. Draw trough levels immediately prior to next dose. Steady-state levels are reached within two to three days in patients taking oxcarbazepine twice daily

Storage Instructions:

Room temperature

Stability Requirements:



Room temperature

14 days


14 days


105 days

Freeze/thaw cycles

Stable x3

Rejection Criteria:

Gross lipemia; hemolysis; icteric specimen; gel-barrier tube

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MCI Diagnostic

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Tulsa, Oklahoma 74136

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Sun: 7AM-3PM

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Mon – Sat: 7AM-11PM

Sun: 7AM-3PM


Mon – Sat: 7AM-11PM

Sun: 7AM-3PM

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