Oxcarbazepine (Trileptal)
Test ID:
703888
CPT code:
80183
Synonyms:
GP 47680
Trileptal®
Oxcarbazepine, Serum or Plasma
Clinical Use:
Oxcarbazepine is an antiepileptic drug, indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy. It is used in adjunctive therapy in epileptic children between the ages of four and 16.
Test Information:
Oxcarbazepine is the prodrug for its active metabolite, 10-hydroxy-carbamazepine (MHD). MHD reaches maximal serum concentrations in three to five hours after oral ingestion and is 40% bound to protein. The elimination half-life is 8 to 15 hours. Co-administration of other antiepileptic drugs (eg, carbamazepine, phenytoin, phenobarbital, primidone) causes decreases in MHD serum levels
Specimen Type:
Serum or plasma
Requested Volume:
1 mL
Minimum Volume:
0.3 mL
Container Type:
Serum or plasma
Collection:
Transfer separated serum or plasma to a plastic transport tube. Draw trough levels immediately prior to next dose. Steady-state levels are reached within two to three days in patients taking oxcarbazepine twice daily
Storage Instructions:
Room temperature
Stability Requirements:
Temperature |
Period |
---|---|
Room temperature |
14 days |
Refrigerated |
14 days |
Frozen |
105 days |
Freeze/thaw cycles |
Stable x3 |
Rejection Criteria:
Gross lipemia; hemolysis; icteric specimen; gel-barrier tube
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