Myeloproliferative Neoplasms (MPN) w/Hypereosinophilia FISH
•Chronic Myeloid Neoplasm
Confirmation/identification of chromosome abnormalities in interphase nuclei. Leukemia monitoring of residual disease.
Bone marrow, blood, cerebrospinal fluid (CSF), FNA, bone marrow touch prep slides.
Fixed-cell pellet from a cytogenetic analysis, three slides, 5 mL blood (adults) or 1 mL bone marrow (For additional cytogenetic studies, an additional 1 mL of bone marrow is required.)3 mL bone marrow (For additional cytogenetic studies an additional 1 mL of bone marrow is required.), fixed-cell pellet, three slides.
Green-top (heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube
Maintain specimens at room temperature.
Broken or dirty slides; excessive cellular debris; stains on slides.
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