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Multiple Myeloma FISH Panel

Test ID: 


CPT code:

88271 (x5), 88275


  • Monoclonal Gammopathy of Undetermined Significance (MGUS)
  • Plasma Cell Leukemia

Clinical Use:

Diagnostic test for multiple myeloma. Plasma cell enrichment diagnosis increased as much as 50% to 100%. The FISH results on the enriched assay should not be used as a quantitative assay, since the abnormal cells do not represent the percentage of abnormal cells in the aspirate.

Specimen Type:

Bone marrow

Requested Volume: 

1 to 3 mL bone marrow

Minimum Volume: 

1 mL bone marrow

Container Type: 

Green-top (sodium heparin) tube with bone marrow aspirate.


Transport to the testing lab at room temperature; use a cool pack. Do not allow sample to freeze. Sample must arrive in the laboratory within 72 hours of collection.

Storage Instructions:

Maintain specimen at room temperature.

Rejection Criteria

Whole blood; broken Vacutainer®; specimen received at testing facility 72 hours after collection

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MCI Diagnostic

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Sun: 7 AM-3 PM

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