Test ID: 


CPT code:



Mn, Urine

Clinical Use:

Confirm manganese exposure, toxicity, or poisoning by documenting excessive urine excretion of the metal. Also used to individualize manganese dosing in long-term parenteral nutrition, especially in liver disease, when biliary excretion is low, or when there is excessive gastrointestinal losses, such as in short bowel syndrome. Has been used to follow the success of chelation therapy with para-aminosalicylate sodium in manganism.

Test Information:

Manganese poisoning through acute exposure may produce symptoms of fever, muscle pains, chills, and dryness of the mouth and throat. Chronic exposures to manganese may be evidenced by effects on the CNS (eg, headache, restlessness, irritability, personality change, hallucinations, and hearing impairment). Levels may be reduced mildly in epilepsy and raised in hepatitis or jaundice. Urine manganese is used in conjunction with plasma manganese to evaluate possible toxicity or deficiency of manganese, an essential mineral. High concentrations can cause nausea, headache, and psychiatric disturbances with neurological damage similar to Parkinson disease. Normalization of plasma may not reverse the neurological damage.

Specimen Type:

Urine (random)

Requested Volume: 

20 mL

Minimum Volume: 

1.7 mL

Container Type: 

Plastic urine container, no preservative

Storage Instructions:

Maintain specimen at room temperature.

Stability Requirements:



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3



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MCI Diagnostic

Providing top patient care with fast results. 

7018 South Utica Avenue

Tulsa, Oklahoma 74136

Hours of Operation

Mon – Sat: 7AM-11PM

Sun: 7AM-3PM

Government Contract

Mon – Sat: 7AM-11PM

Sun: 7AM-3PM


Mon – Sat: 7AM-11PM

Sun: 7AM-3PM

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