LC-1 (Liver Cytosol Protein-1)

Test ID: 

706636

CPT code:

86376

Synonyms:

LKM
LKM-1 Antibodies

Clinical Use:

The detection of LKM-1 antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH-2). LKM antibodies are markers of AIH-2 which usually begins in childhood and generally affects children younger than 18 years of age. LKM antibodies are associated with a more serious progression of the disease. The disease is most common between the ages of 2 to 14 and is more frequent in females than males (8:1). LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection.

Specimen Type:

Serum

Requested Volume: 

1 mL

Minimum Volume: 

0.3 mL

Container Type: 

Red-top tube or gel-barrier tube

Collection:

To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions:

Maintain specimen at room temperature no longer than eight hours. Sample can be refrigerated for 48 hours. For longer storage, freeze sample at -20°C or lower.

Rejection Criteria

Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added

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MCI Diagnostic

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