Interleukin-10 (IL-10) is an important suppressor of immune responses In vitro studies indicate that IL-10 directly inhibits IL-2 and IL-5 production by TH1 and TH2 cells. IL-10 acts as an immunosuppressor of antigen presenting cells (APC). IL-10 suppresses epidermal Langerhans cell APC function, monocyte chemokines expression, and the bactericidal responses of macrophages. A number of studies suggest that IL-10 plays a role in controlling inflammation, autoimmunity, and angiogenesis.
Lavender-top (EDTA) tube
Separate serum from cells. Transfer serum to a plastic transport tube.
Stable at room temperature or frozen for 14 days. Freeze/thaw cycles x3.
Gross hemolysis; sample left on cells
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