Interleukin-10, Serum

Test ID: 

705484

CPT code:

83520

Synonyms:

IL-10

IL10

Clinical Use:

Interleukin-10 (IL-10) is an important suppressor of immune responses In vitro studies indicate that IL-10 directly inhibits IL-2 and IL-5 production by TH1 and TH2 cells. IL-10 acts as an immunosuppressor of antigen presenting cells (APC). IL-10 suppresses epidermal Langerhans cell APC function, monocyte chemokines expression, and the bactericidal responses of macrophages. A number of studies suggest that IL-10 plays a role in controlling inflammation, autoimmunity, and angiogenesis.

Specimen Type:

Serum

Requested Volume: 

0.5 mL

Minimum Volume: 

0.3 mL

Container Type: 

Lavender-top (EDTA) tube

Collection:

Separate serum from cells. Transfer serum to a plastic transport tube.

Storage Instructions:

Refrigerate

Stability Requirements:

 Stable at room temperature or frozen for 14 days. Freeze/thaw cycles x3.

Rejection Criteria

Gross hemolysis; sample left on cells