Infliximab+Ab (Serial Monitor)

Test ID: 

703763

CPT code:

80299, 82397

Synonyms:

Infliximab and Anti-Infliximab Antibody (Serial Monitor), DoseASSURE™ IFX

Anti-TNF-alpha Drug

DoseASSURE

IFD

Remicade

Infliximab and Anti-Infliximab Antibody, DoseASSURE™ IFX

Clinical Use:

Provides infliximab drug concentration levels as well as levels of anti-infliximab antibodies.

Test Information:

In the absence of anti-infliximab antibodies, the infliximab drug level typically reflects the total infliximab concentration in serum. In the presence of anti-infliximab antibodies, the infliximab drug level typically reflects the antibody-unbound fraction of infliximab concentration in serum. The presence of infliximab drug, even at concentrations well above target treatment levels (>50 μg/mL), does not interfere with the anti-infliximab antibody detection. This assay may be helpful for any patients on infliximab therapy for diseases such as Crohn’s disease, inflammatory bowel disease, ulcerative colitis, rheumatoid arthritis, or other autoimmune conditions.

Specimen Type:

Serum

Requested Volume: 

2 mL

Minimum Volume: 

1 mL

Container Type: 

Red-top tube or gel-barrier tube

Collection:

Allow a minimum clotting time of 30 to 60 minutes with serum separation within 2 hours of collection. Send serum in a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions:

Frozen (preferred) or refrigerated

Stability Requirements:

Stable at room temperature or refrigerated for seven days. Freeze/thaw cycle: stable x6

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MCI Diagnostic

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7018 South Utica Avenue

Tulsa, Oklahoma 74136

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