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Immune Complexes, C1q Binding

Test ID: 


CPT code:



C1q Binding

C1q Binding Test

C1q Immune Complexes

Circulating Immune Complexes

Complement C1q Immune Complexes

Immune Complex Detection by C1q

Clinical Use:

Monitor immune complex disease (ie, lupus, glomerulonephritis, serum hepatitis, arthritis, vasculitis); monitor progress of some malignancies

Test Information:

Circulating immune complexes can be demonstrated in rheumatic, infectious, and neoplastic diseases, as well as most immunologically mediated illnesses (inflammatory bowel disease, thrombotic thrombocytopenic purpura). The 1981 WHO/IUIS survey of laboratory tests in clinical immunology concluded that the detection of circulating immune complexes is not essential to any specific diagnosis.

Specimen Type:

Serum, frozen

Requested Volume: 

1 mL

Minimum Volume: 

0.1 mL

Container Type: 

Red-top tube or gel-barrier tube


Separate serum from cells. Transfer specimen to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions:

Freeze prior to transport.

Stability Requirements:

Samples may be stored at 2°C to 8°C for seven days prior to testing.

Rejection Criteria

Hemolysis; heating specimen for thawing may give false-positive results, avoid repeated thawing and freezing.

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