Immune Complexes, C1q Binding
C1q Binding Test
C1q Immune Complexes
Circulating Immune Complexes
Complement C1q Immune Complexes
Immune Complex Detection by C1q
Monitor immune complex disease (ie, lupus, glomerulonephritis, serum hepatitis, arthritis, vasculitis); monitor progress of some malignancies
Circulating immune complexes can be demonstrated in rheumatic, infectious, and neoplastic diseases, as well as most immunologically mediated illnesses (inflammatory bowel disease, thrombotic thrombocytopenic purpura). The 1981 WHO/IUIS survey of laboratory tests in clinical immunology concluded that the detection of circulating immune complexes is not essential to any specific diagnosis.
Red-top tube or gel-barrier tube
Separate serum from cells. Transfer specimen to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Freeze prior to transport.
Samples may be stored at 2°C to 8°C for seven days prior to testing.
Hemolysis; heating specimen for thawing may give false-positive results, avoid repeated thawing and freezing.