17-OH Progesterone/Creatinine Ratio, Random Urine
17-Hydroxyprogesterone (17-OHP) in urine is greatly elevated in patients with polycystic ovarian disease and in patients with idiopathic hirsutism. Wong and coworkers showed that measurement of 17-OHP in 24-hour urine produced results that may be useful for monitoring glucocorticoid and mineralocorticoid therapy in patients with congenital adrenal hyperplasia (CAH).1 Other studies have shown that 17-OHP in 24-hour urine correlated well with serum 17-OHP and suggested that the urine measurement of 17-OHP may be a reliable alternative to serum 17-OHP measurement for monitoring of CAH therapy.
30 mL aliquot
4 mL aliquot
Use random urine transport tube containing 6N HCl or urine Monovette® with pH stabilizer. Monovette® instructions accompany units. Preservative must be added to the container prior to the start of the collection. If collecting without Monovette®, use plastic urine container and adjust urine pH to <5 with 6N HCl. Caution: Strong acid. May cause skin burns.
Specimen with no preservative; original container with pH >5