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HSV 1 AND 2-Specific AB, IGG

Test ID: 


CPT code:

86695, 86696


Herpes Simplex Virus (HSV) Types 1 and 2, IgM Antibodies, Indirect

Clinical Use:

Semiquantitative detection of IgM antibodies to herpes 1 and 2

Test Information:

By design, all HSV indirect immunofluorescent antibody assays cannot be type-specific. The test is created using cell culture in which HSV type 1 or type 2 has been grown and infected some, but not all, of the cells present. When serum is reacted with this antigenic substrate, the antibodies formed by the patient will include both those that are type-specific as well as antibodies to shared not type-specific antigens of HSV-1 and HSV-2. Because of these shared antigens, many cross-reacting antibodies are formed. Elevated titers to both HSV-1 and HSV-2 may represent cross-reactive HSV antibodies rather than exposure to both HSV-1 and HSV-2.

Specimen Type:


Requested Volume: 

1 mL

Minimum Volume: 

0.3 mL

Container Type: 

Red-top tube or gel-barrier tube

Storage Instructions:

Room temperature

Stability Requirements:



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Rejection Criteria

Lipemia; hemolysis; bacterial contamination

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