Hemophilia A Monitoring Profile
Nonsevere Hemophilia A Profile
This profile is appropriate for the evaluation of individuals suspected of or previously identified as having nonsevere (mild or moderate) hemophilia A, in order to determine if there is a twofold discrepancy in the one stage and chromogenic factor VIII activities as has been described in discrepant hemophilia A. Evaluation for nonsevere hemophilia A using a one stage (clot-based) activity assay only may lead to missed diagnosis or misclassification of disease severity.
Additional Test Information:
aPTT; factor VIII activity; factor VIII chromogenic; pathologist interpretation
4 mL platelet-poor, frozen, citrated plasma divided into two tubes
Blue-top (sodium citrate) tube
Plasma must be separated from cells within three hours of venipuncture and plasma centrifuged a second time before being placed in plastic transport tubes. Freeze within four hours and keep frozen until testing is performed.
Noncitrated plasma; gross hemolysis; fibrin clot in plasma; sample received thawed