Galectin-3
Test ID:
702945
CPT code:
82777
Clinical Use:
For use in conjunction with clinical evaluation as an aid in assessing the prognosis of patients with chronic heart failure. Galectin-3 levels >17.8 ng/mL are present in a proportion of patients with NYHA class II-IV. Such elevated levels are associated with a more progressive form of heart failure resulting in an increased hazard for death or hospitalization.
Test Information:
Galectin-3 is member of the protein family known as galectins. Galectins bind to certain carbohydrates via specific carbohydrate recognition domains (CRDs). Galectin-3 is a 29 to 35 kDa chimera-type galectin − the only member of the galectin family with an extended N-terminal domain constituted of tandem repeats of short amino acid segments (a total of 110-130 amino acids) linked to a single C-terminal CRD of about 130 amino acids.
Specimen Type:
Serum or plasma
Requested Volume:
0.8 mL
Minimum Volume:
0.4 mL
Container Type:
Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube
Collection:
Transfer separated serum or plasma to a plastic transport tube.
Storage Instructions:
Room temperature. Stable at room temperature or refrigerated for 22 days, or frozen for 12 months. Freeze/Thaw Cycle: Stable x9
Rejection Criteria
Visible hemolysis; plasma other than EDTA; improperly labeled specimen
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