Everolimus, Screen
Test ID:
703710
CPT code:
80169
Clinical Use:
Everolimus is a proliferation signal inhibitor that prevents allograft rejection. It exerts its immunosuppressive effect by inhibiting the proliferation, and thus clonal expansion, of antigen-activated T cells, which is driven by T-cell-specific interleukins. Everolimus inhibits an intracellular signaling pathway that is triggered up binding of these T-cell growth factors to their respective receptors, and which normally leads to cell proliferation. The blockage of this signal by everolimus leads to an arrest of the cells at the G1 stage of cell cycle.
Specimen Type:
Whole Blood
Requested Volume:
2 mL
Minimum Volume:
0.5 mL
Container Type:
Lavender-top (EDTA) tube or green-top (heparin) tube
Storage Instructions:
Room temperature
Stability Requirements:
Temperature |
Period |
---|---|
Room temperature |
14 days |
Refrigerated |
14 days |
Frozen |
14 days |
Freeze/thaw cycles |
Stable x3 |
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MCI Diagnostic
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7018 South Utica Avenue
Tulsa, Oklahoma 74136
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