Dibucaine Number Cholinesterase
Assess the presence of homozygous or heterozygous “atypical” cholinesterase variant, in patients who have low result of serum or plasma cholinesterase assay, and may be at risk of apnea when given succinylcholine muscle relaxant
This approach to detection of serum or plasma cholinesterase variants does not entirely avoid the problem of variation in reactivity with some atypical enzymes.
Serum or plasma
2 mL serum and 5 mL whole blood
0.1 mL serum and 1 mL whole blood
Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube
Do not collect within 24 hours of administration of muscle relaxant.
Separate serum or plasma from cells and place in transport tube. Mark transport tube appropriately “serum” or “plasma.”
Plasma or serum not separated from cells; frozen whole blood received; hemolysis