Diabetes Autoimmune Profile

Test ID:

704349

CPT code:

86337, 83519, 86341 (x2)

Clinical Use:

Diabetes autoantibodies assessment is helpful in identifying and managing patients at risk for development of type 1 diabetes. Published positivity rates for diabetes autoantibodies in new-onset type 1 diabetes patients listed below are based on the combined analysis of GAD-65, ICA 512, insulin antibodies, and ZnT8 antibodies.

Positive rate in new-onset type 1 diabetes patients:

• GAD-65 antibodies = 68% positive

• ICA 512 antibodies = 72% positive

• Insulin antibodies = 55% positive

• ZnT8 antibodies = 63% positive

An increase in the number of positive antibodies is associated with a higher likelihood of type 1 diabetes.

Specimen Type:

Serum, frozen

Requested Volume:

2.5 mL

Minimum Volume:

1.0 mL (Note: This volume does not allow for repeat testing.)

Container Type:

Red-top tube or gel-barrier tube

Collection:

Transfer specimen to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple test on frozen samples, please submit separate frozen specimens for each test requested.