Citric Acid/Creat Ratio, Rand

Test ID: 


CPT code:

82507; 82570


Citric Acid (Citrate):Creatinine Ratio, Random Urine

Citrate Excretion, Urine

Clinical Use:

A timed 24-hour urine collection is the preferred specimen for measuring and interpreting this urinary analyte. Random collections normalized to urinary creatinine may be of some clinical use in patients who cannot collect a 24-hour specimen, typically small children. The mean urinary citrate excretion rate in patients with idiopathic calcium urolithiasis has been found to be significantly lower than that of control groups. Hypocitraturia is common in patients with urolithiasis resulting from renal tubular acidosis and in patients with enteric hyperoxaluria. Citrate excretion is low in renal insufficiency.

Specimen Type:

Urine (random), acidified or frozen

Requested Volume: 

10 mL

Minimum Volume: 

2.5 mL

Container Type: 

Use random urine transport tube or urine Monovette® with pH stabilizer. Monovette® instructions accompany units.


Collect urine and transfer to a random urine transport tube or urine Monovette® with pH stabilizer. Alternatively, the sample may be frozen without added acid.

Storage Instructions:

Refrigerate at 2°C to 8°C.

Stability Requirements:



Room temperature

7 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Rejection Criteria

Acetic or boric acid used as a preservative

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