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C1 Esterase Inhibitor, Func

Test ID: 


CPT code:



C1 Esterase Inhibitor
C1 Inactivator
C1 Inhibitor
Esterase Inhibitor
Hereditary Angioneurotic Edema Test

Clinical Use:

Esterase inhibitor is decreased in hereditary angioneurotic edema. Functional level will be decreased when concentration of inhibitor is decreased or inhibitor is nonfunctional.

Additional Test Information:

Enzyme immunoassay (EIA) to measure functional activity. This method provides C1 esterase function activity as a percentage of mean normal activity.

Specimen Type:

Serum or plasma, frozen

Requested Volume: 

0.1 mL

Minimum Volume: 

0.5 mL

Container Type: 

Red-top tube or lavender-top (EDTA) tube


Separate serum or plasma from cells and transfer to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions:

Freeze (A serum sample should not be stored at room temperature [15°C to 30°C] for longer than six hours. EDTA plasma may be held at room temperature for 24 hours.)

Rejection Criteria

Plasma other than EDTA; thawed or nonfrozen sample

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