Test ID: 


CPT code:

81206; 81207


Acute Lymphocytic Leukemia

BCR-ABL1 Transcript Detection by RT-PCR

Quantitative-Chronic Myelogenous Leukemia

BCR-ABL1 Transcript Detection by RT-PCR

Quantitative – Quantitative BCR-ABL1 Translocation Detection by RT-PCR for CML and ALL

Clinical Use:

This assay can detect three different types of BCR-ABL1 fusion transcripts associated with CML, ALL, and AML:e13a2 (previously b2a2) and e14a2 (previously b3a2) (major breakpoint, p210), as well as e1a2 (minor breakpoint, p190). The e13a2 and e14a2 transcript values are titrated to the current International Scale (IS). The standardized baseline is 100% BCR-ABL1 (IS) and major molecular response (MMR) is equivalent to 0.1% BCR-ABL1 (IS) corresponding to a 3-log reduction. Results should be correlated with appropriate clinical and laboratory information as indicated.

Specimen Type:

Whole blood, bone marrow, or cell pellet

Requested Volume: 

5 mL whole blood  OR

2 mL bone marrow

Minimum Volume: 

3 mL whole blood OR

1 mL bone marrow

Container Type: 

Lavender-top (EDTA) tube, green-top (sodium heparin) tube, or yellow-top (ACD-A) tube


Submit at room temperature. Specimens should arrive in the laboratory within 48 hours of collection. Indicate date and time of collection on test request form.

Storage Instructions:

Submit at room temperature. If specimen has to be stored more than 48 hours, refrigerate at 2°C to 8°C.

Rejection Criteria

Specimen does not meet collection criteria; frozen whole blood or marrow; leaking tube; clotted blood or marrow; grossly hemolyzed; otherwise visibly degraded; contamination by another specimen; containing suspicious foreign material

Return Back to Test Directory

MCI Diagnostic

Providing top patient care with fast results. 

7018 South Utica Avenue

Tulsa, Oklahoma 74136

Hours of Operation

Mon – Sat: 7AM-11PM

Sun: 7AM-3PM

Government Contract

Mon – Sat: 7AM-11PM

Sun: 7AM-3PM


Mon – Sat: 7AM-11PM

Sun: 7AM-3PM

Thank you for uploading your files. Your upload has been submitted successfully.