Apolipoprotein B

Test ID: 

702783

CPT code:

82172

Synonyms:

Beta Apolipoprotein

Clinical Use:

LDL and its major protein, apolipoprotein B, play an essential role in lipid transport and metabolism. Apo B may regulate cholesterol synthesis through its interaction with specific cell membrane receptors and by inhibition of HMG Co A reductase. This enzyme has been identified as the rate controlling enzyme in cholesterol biosynthesis. Apo B may be important in the genesis of atherosclerosis and its quantitation useful in the evaluation of patients at risk for or having coronary atherosclerosis (CAD). High levels indicate increased risk for CAD.

Specimen Type:

Serum (preferred) or plasma

Requested Volume: 

2 mL

Container Type: 

Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube

Patient Preparation: 

Patient must be fasting 12 to 14 hours.

Collection:

Separate serum or plasma from cells. Transfer specimen to a plastic transport tube.

Storage Instructions:

Maintain specimen at room temperature.

Stability Requirements:

Rejection Criteria

Specimen from nonfasting patient