Antiscleroderma – 70 Antibodies

Test ID: 


CPT code:



Anti-Scl 70

Clinical Use:

Differential diagnosis of scleroderma (progressive systemic sclerosis)

Test Information:

Scl-70 antibody is seen in 20% of patients with scleroderma, and in some patients with CREST syndrome (calcinosis, Raynaud, esophageal dysfunction, sclerodactyly, telangiectasia). These syndromes are also associated with a high frequency of speckled pattern immunofluorescent antinuclear antibody tests. Scl-70 may identify a subset of scleroderma patients with severe skin, joint, and lung disease. In addition, the presence of Scl-70 in Raynaud phenomenon may indicate a poor prognosis.

Specimen Type:


Requested Volume: 

1 mL 

Minimum Volume: 

0.5 ml (Note: This volume does not allow for repeat testing.)

Container Type: 

Red-top tube or gel-barrier tube

Storage Instructions:

Room temperature:

Stability Requirements:



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Rejection Criteria

Hemolysis; icterus; lipemia; gross bacterial contamination

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MCI Diagnostic

Providing top patient care with fast results. 

7018 South Utica Avenue

Tulsa, Oklahoma 74136

Hours of Operation

Mon – Sat: 7AM-11PM

Sun: 7AM-3PM

Government Contract

Mon – Sat: 7AM-11PM

Sun: 7AM-3PM


Mon – Sat: 7AM-11PM

Sun: 7AM-3PM

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