Antimyeloperoxidase (MPO) Antibodies

Test ID: 

704716

CPT code:

83520

Synonyms:

Anti-MPO Antibodies/pANCA-specific Antibody

Clinical Use:

For diagnosis and monitoring inflammatory activity in primary systemic small vessel vasculitides. The anti-MPO-ANCA EIA is useful for confirming positive ANCA results by IFA, particularly with the pANCA pattern. Presence of anti-MPO antibodies is highly specific for idiopathic and vasculitis-associated crescentic glomerulonephritis, classic polyarteritis nodosa, Churg-Strauss syndrome, and polyangiitis overlap syndrome without renal involvement. Levels of anti-MPO are elevated during active phases of disease and lower during remission. Therefore, monitoring anti-MPO levels can aid in disease management.

Specimen Type:

Serum

Requested Volume: 

0.6 mL

Minimum Volume: 

0.3 mL

Container Type: 

Red-top tube or gel-barrier tube

Storage Instructions:

Room temperature

Stability Requirements:

Rejection Criteria

Hemolysis; lipemia; gross bacterial contamination