Antimitochondrial Antibody (AMA), Quantitative
Test ID:
705996
CPT code:
83516
Synonyms:
AMA
Clinical Use:
The presence of mitochondrial antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of primary biliary cirrhosis (PBC).
Test Information:
Antimitochondrial antibodies (AMA) have been reported in 90% to 96% of patients with primary biliary cirrhosis. AMA are also occasionally found in sera of patients with other liver diseases, including chronic active hepatitis, cryptogenic cirrhosis, as well as in patients with clinical but no biochemical evidence of liver disease. The M2 antigen used is strongly associated with PBC, while other types (M1, M2, M5, and M6) are associated with a wide variety of conditions.
Specimen Type:
Serum
Requested Volume:
1 mL
Minimum Volume:
0.3 mL
Container Type:
Red-top tube or gel-barrier tube
Storage Instructions:
Room temperature:
Stability Requirements:
Temperature |
Period |
---|---|
Room temperature |
14 days |
Refrigerated |
14 days |
Frozen |
14 days |
Freeze/thaw cycles |
Stable x3 |
Rejection Criteria
Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added
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