Antichromatin Antibodies

Test ID: 

705991

CPT code:

86235

Synonyms:

•Antibodies to LE Cell Phenomenon

Clinical Use:

Help to diagnose drug-induced lupus (DIL) and systemic lupus erythematosus (SLE). Antibodies to both chromatin and histones have been found in patients with procainamide-induced lupus; however, patients with lupus induced by drugs such as quinidine, penicillamine, methyldopa, and acebutolol have antibodies to chromatin but not antihistone. Antichromatin antibodies are found in 50% to 90% of SLE patients and have been linked with proteinuria in SLE patients.

Specimen Type:

Serum

Requested Volume: 

1 mL

Minimum Volume: 

0.5 ml (Note: This volume doesnot allow for repeat testing.)

Container Type: 

Gel-barrier tube or red-top tube

Collection:

If tube other than gel-barrier tube is used, transfer the separated serum to a plastic transport tube

Storage Instructions:

Room temperature

Stability Requirements:

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Rejection Criteria

Hemolysis

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