Antichromatin Antibodies
Test ID:
705991
CPT code:
86235
Synonyms:
•Antibodies to LE Cell Phenomenon
Clinical Use:
Help to diagnose drug-induced lupus (DIL) and systemic lupus erythematosus (SLE). Antibodies to both chromatin and histones have been found in patients with procainamide-induced lupus; however, patients with lupus induced by drugs such as quinidine, penicillamine, methyldopa, and acebutolol have antibodies to chromatin but not antihistone. Antichromatin antibodies are found in 50% to 90% of SLE patients and have been linked with proteinuria in SLE patients.
Specimen Type:
Serum
Requested Volume:
1 mL
Minimum Volume:
0.5 ml (Note: This volume doesnot allow for repeat testing.)
Container Type:
Gel-barrier tube or red-top tube
Collection:
If tube other than gel-barrier tube is used, transfer the separated serum to a plastic transport tube
Storage Instructions:
Room temperature
Stability Requirements:
Temperature |
Period |
---|---|
Room temperature |
14 days |
Refrigerated |
14 days |
Frozen |
14 days |
Freeze/thaw cycles |
Stable x3 |
Rejection Criteria
Hemolysis
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