Anti-Jo-1

Test ID: 

704714

CPT code:

86235

Synonyms:

Polymyositis/t-RNA Synthtase

Clinical Use:

Evaluate patients suspected of having polymyositis, dermatomyositis, or polymyositis-scleroderma overlap syndrome

Test Information:

Anti-Jo-1 antibodies are present in approximately 20% to 30% of patients with adult-onset polymyositis syndromes. They are present in >65% of patients with both myositis and interstitial lung disease. In such patients, the presence of anti-Jo-1 antibodies may be predictive of a response to steroid treatment. Testing for ANAs is not adequate for the detection of anti-Jo-1 antibodies.

Specimen Type:

Serum

Requested Volume: 

0.6 mL

Minimum Volume: 

0.3 mL

Container Type: 

Red-top tube or gel-barrier tube

Storage Instructions:

Room temperature

Stability Requirements:

Expected Turnaround Time:

1 to 2 Days

Rejection Criteria

Hemolysis; icterus; lipemia; bacterial contamination