Androstenedione is useful when evaluating patients with androgen excess and managing patients with Congenital Adrenal Hyperplasia (CAH
Androstenedione (also known as 4-androstenedione and δ4-androstenedione) is a 19-carbon steroid hormone produced in the adrenal glands and the gonads that is the common precursor in the biochemical pathway that produces the androgen testosterone and the estrogens estrone and estradiol.1
Red-top tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the steroid by the gel. Depending on the specimen volume and storage time, the decrease in androstenedione level due to absorption may be clinically significant.
Transfer separated serum to a plastic transport tube.
Room temperature: 14 days
Refrigerated: 28 days
Frozen: 2 years
Gross hemolysis; lipemia; gel-barrier tube
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