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Alpha-1-Acid Glycoprotein

Test ID: 


CPT code:



Alpha-1-Acid Glycoprotein

Clinical Use:

Monitor acute-phase proteins associated with inflammatory conditions such as RA and malignant neoplasms.

Additional Test Information:

As an acute-phase protein levels of α1-acid glycoprotein are elevated during infections as well as acute and chronic inflammatory processes (eg, Crohn’s disease). In these cases a highly sensitive assessment of the condition of the patient can be obtained by preparing a prognostic index of α1-acid glycoprotein and other parameters such as CRP.1-3 Patients with injuries, burns, or tumors exhibit elevated concentrations. Patients with chronic renal failure are found to have high concentrations of α1-acid glycoprotein, with no major difference reported between dialyzed and nondialyzed patients. Diminished concentrations due to restricted production of α1-acid glycoprotein are found in patients with chronic liver diseases. Low serum concentrations due to increased excretion of the protein are associated with nephritic syndrome.

Specimen Type:

Serum or plasma

Requested Volume: 

1 mL

Minimum Volume: 

0.4 mL

Container Type: 

Red-top tube, gel-barrier tube, or green-top (heparin) tube


Separate serum or plasma from red blood cells.

Storage Instructions:

Room temperature

Rejection Criteria

Gross lipemia that cannot be cleared by ultracentrifugation; heat-inactivated samples

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