Monitor acute-phase proteins associated with inflammatory conditions such as RA and malignant neoplasms.
Additional Test Information:
As an acute-phase protein levels of α1-acid glycoprotein are elevated during infections as well as acute and chronic inflammatory processes (eg, Crohn’s disease). In these cases a highly sensitive assessment of the condition of the patient can be obtained by preparing a prognostic index of α1-acid glycoprotein and other parameters such as CRP.1-3 Patients with injuries, burns, or tumors exhibit elevated concentrations. Patients with chronic renal failure are found to have high concentrations of α1-acid glycoprotein, with no major difference reported between dialyzed and nondialyzed patients. Diminished concentrations due to restricted production of α1-acid glycoprotein are found in patients with chronic liver diseases. Low serum concentrations due to increased excretion of the protein are associated with nephritic syndrome.
Serum or plasma
Red-top tube, gel-barrier tube, or green-top (heparin) tube
Separate serum or plasma from red blood cells.
Gross lipemia that cannot be cleared by ultracentrifugation; heat-inactivated samples
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