Acetylcholinesterase (AChE), Amniotic Fluid With Reflex

Test ID: 

704607

CPT code:

82013

Synonyms:

•AChE
•Amniotic Fluid With Reflex to Hb F

Clinical Use:

Analysis of midtrimester amniotic fluid for detection of open neural tube defects and ventral wall defects.

Additional Test Information:

The patient’s gestational age must be at least 13 weeks for accurate AChE detection. Optimal gestational age is 14 to 18 weeks. Include the gestational age by ultrasound and/or last menstrual period (LMP) on the request form.

Specimen Type:

Amniotic fluid

Requested Volume: 

3 mL

Container Type: 

Sterile plastic conical tube; do not use urine containers or tubes with rubber stoppers. Rubber is toxic to amniocyte

Patient Preparation: 

The patient should have undergone ultrasound studies to verify fetal viability, detect multiple gestation, confirm gestational age, localize placenta, and detect fetal and uterine pathology.

Collection:

Avoid contamination of amniotic fluid with maternal or fetal blood. As little as one drop of fetal blood can cause false-positive results during assay of amniotic fluid. Amniotic fluid should be collected by the attending physician.

Storage Instructions:

Ship and maintain specimen at room temperature.

Rejection Criteria

Specimen found not to be amniotic fluid; gross contamination of amniotic fluid with maternal or fetal blood; quantity not sufficient for analysis.

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